Teratogenic Potential of NiCl2 in Fetal Mice

Teratogenic Effects of Pregabalin in Mice

  Objective(s): Anti-epileptic drugs (AEDs) have the potential to affect fetal development throughout pregnancy. Considering the broad therapeutic indications of pregabalin (PGB), its potential teratogenic effects and the levels of homocysteine have been studied.   Materials and Methods: Timed-pregnant mice received one of three doses of PGB (20, 40 or 80 mg/kg/day) or the vehicl...

Teratogenic Effects of Long Term Consumption of Potassium Benzoate on Eye Development in Balb/c Fetal Mice

Teratogenic effect of Lippia citriodora leaves aqueous extract in mice

Objective: Safety of Lippia citriodora, as a herbal remedy, in pregnancy has not yet been evaluated. This study aimed to identify the effect of L. citriodora aqueous extract on pregnancy outcome in mice. Materials and Methods: Timed-pregnant mice received doses of 0.5 g/kg/day L. citriodora aqueous extract or the vehicle control during organogenesis, intraperitoneally. Maternal body weights wer...

Teratogenic Effects of Carbamazepine in Mice

OBJECTIVES The aim of this study was to determine the teratogenic effects of carbamazepine (CBZ) in BALB/c mice. MATERIALS AND METHODS Mature female and male BALB/c mice (25-30 g) were used for all experiments. After standardization of administration and dose of CBZ, animals in the CBZ-treated groups (CBZ 450 mg/kg and 600 mg/kg) were fed on medicinal diet. The dams in the control group were ...

teratogenic effects of pregabalin in mice

objective(s): anti-epileptic drugs (aeds) have the potential to affect fetal development throughout pregnancy. considering the broad therapeutic indications of pregabalin (pgb), its potential teratogenic effects and the levels of homocysteine have been studied.   materials and methods: timed-pregnant mice received one of three doses of pgb (20, 40 or 80 mg/kg/day) or the vehicle control during ...